Careers

Senior Medical Director

Company Overview

ArriVent is a clinical-stage biopharmaceutical company with employees across the US and sites in Gaithersburg MD and Burlingame CA. We are dedicated to the identification, development and commercialization of differentiated medicines to address the unmet medical needs of patients with cancers. ArriVent seeks to utilize its team’s deep drug development experience to maximize the potential of its lead development candidate, firmonertinib, and advance a pipeline of novel therapeutics, such as next-generation antibody drug conjugates, through approval and commercialization in patients suffering from cancer, with an initial focus on solid tumors.

Position Summary

The Senior Medical Director provides clinical scientific leadership for programs including direct responsibility for clinical development strategy and execution of clinical trials. You will lead multi-disciplinary teams charged with guiding clinical development and subsequent regulatory submissions.  This position reports to the SVP, Head of Clinical Development.  As the cross-functional team is based in the San Francisco Bay Area with travel required to the Burlingame CA office and video meetings with Asian partners, this position is based in the Pacific Time zone.

Key Responsibilities

• Design robust and innovative clinical development plans for Phase 1 or 2 programs.
• Interact effectively and successfully with regulatory agencies.
• Serve as the program Medical Monitor while working in a cross functional environment with representatives from other involved line functions and lead teams towards sound decision-making.
• Lead the development of clinical study protocols, protocol amendments, study guides, protocol training materials and other clinical study related documents based on the global development plan.
• Perform medical monitoring, responses to site inquiries, and work with CRO medical monitors when appropriate.
• Cultivate and nurture strong collaborations with key opinion leaders, investigators, CROs, research centers and corporate partners.
• Medical lead in data analysis and interpretation, reporting and communication to ensure consistency and relevance of medical content and scientific messages across Clinical Study Report, health authority briefing books, and NDA/BLA submission documents, etc.
• Assist in the evaluation of external opportunities for partnering or licensing new oncology assets.

Education & Experience

• MD or MD/PhD with Oncology (solid tumor) or relevant clinical training.
• Minimum of 5 years of industry experience in oncology clinical development, with experience designing, executing, and serving as the Medical Monitor for first-in-human clinical trials.
• Experience with development of antibody-drug conjugates preferred.
• Experience working in a small and dynamic biotech setting.
• Experience developing unique and innovative clinical strategies to significantly shorten the development cycle in the face of an evolving regulatory landscape.
• Demonstrate proven knowledge of compliance and global regulatory requirements (ICH) for development of pharmaceutical candidates / products.
• Familiarity with drug-diagnostic co-development.
• Excellent scientific standing among peers and the ability to address issues with scientific difficulty and creative solutions.